Teenage girl with fever and chest pain

A 16-year old woman comes to her family doctor with a two week history of febrile illness and chest pain. On physical exam she has a erythematous, macular facial rash, and appeared to have warm and tender joints, particularly in her left wrist and elbow. There was a mild anemia and the platelet count was 60,000. The patient was hospitalized for further evaluation. An anti-nuclear antibody (ANA) test was positive with a titer of 1:612.

The correct answer is D. Systemic lupus erythematosus. There were a total of 16 responses. A breakdown of responses are inside the parentheses below.

The most likely diagnosis is:

A. Goodpasture syndrome (0)
B. Sjogren syndrome (0)
C. Scleroderma (1)
D. Systemic lupus erythematosus (15)
E. Dermatomyositis (0)

(see results graphically)