Communication: Discussion Board: Quiz #11 Results What is the most common cause of dementia in the elderly? Alzheimer disease Name the pattern of necrosis in the CNS that is caused by hypotension (e.g., near-downing) and shock (e.g., myocardial infarction). Watershed infarct Symptoms of this disease are cervical rigidity, headache, vomiting and fever. Pathologic findings include accumulation of polymorphonuclear leukocytes (neutrophils) and fibrin in the subarachnoid space or cerebral spinal fluid. Name this disease. Bacterial meningitis A 12-year old girl with a history of otitis media developed a cystic lesion in the temporal lobe. The most probable diagnosis is: Cerebral abscess This chronic demylinating disease of the CNS is probably a consequence of an autoimmune attack on some component of myelin. Name this disease. Multiple sclerosis Name the myelin-producing cells of the central nervous system. Oligodendroglial cells This encephalopathy results from a deficiency of thiamine (vitamin B1) and arises most commonly in association with chronic alcoholism. Name this disease/syndrome. Wenicke syndrome This vascular lesion occurs most commonly at branch points in the vacinity of the Circle of Willis. It is the consequence of a developmental arterial defect. Name this lesion. Berry aneurysm Kuru and Creutzfeldt-Jakob disease are examples of this group of neurodegenerative diseases. They occur sporadically and have heritable forms. What is the name for this group of diseases? Spongiform encephalopathies This highly malignant, glial cell neoplasm shows numerous mitoses, endothelial cell proliferation and necrosis. The most likely diagnosis is: Glioblastoma multiforme